Dual Specificity Phosphatase 1

A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES and JNK MITOGEN-ACTIVATED PROTEIN KINASES.

Also Known As:

3CH134 Phosphatase; CL100 Phosphatase; Externally Regulated Phosphatase (ERP); MAP Phosphatase-1; MAPK Phosphatase; MKP-1 Phosphatase; Map Kinase Phosphatase 1; Mitogen-Activated Protein Phosphatase-1; MAP Phosphatase 1; MKP 1 Phosphatase; Mitogen Activated Protein Phosphatase 1; Phosphatase, 3CH134; Phosphatase, CL100; Phosphatase, MAPK; Phosphatase, MKP-1; Phosphatase-1, MAP; Phosphatase-1, Mitogen-Activated Protein; Protein Phosphatase-1, Mitogen-Activated

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Hydrolases: 2206
    - Esterases: 1594
      - Phosphoric Monoester Hydrolases: 7607
        Protein Tyrosine Phosphatases: 1715
        Dual-Specificity Phosphatases: 302
        Dual Specificity Phosphatase 1: 132
        Phosphoprotein Phosphatases: 1228
        Dual-Specificity Phosphatases: 302
        Dual Specificity Phosphatase 1: 132
        Mitogen-Activated Protein Kinase Phosphatases: 91
        Dual Specificity Phosphatase 1: 132
  - Multifunctional Enzymes: 109
    - Dual-Specificity Phosphatases: 302
      - Dual Specificity Phosphatase 1: 132
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Tyrosine Phosphatases: 1715
      - Dual-Specificity Phosphatases: 302
        Dual Specificity Phosphatase 1: 132
    - Phosphoprotein Phosphatases: 1228
      - Dual-Specificity Phosphatases: 302
        Dual Specificity Phosphatase 1: 132
    - Mitogen-Activated Protein Kinase Phosphatases: 91
      - Dual Specificity Phosphatase 1: 132

Jessica R Hammond Selected Research

Jessica R Hammond Research Topics

Disease

Drug/Important Bio-Agent (IBA)